MovDisordV3, Main, Exploration, bibRecord, 001C28

Incidental Lewy body disease: Clinical comparison to a control cohort

Identifieur interne : 001C28 ( Main/Exploration ); précédent : 001C27; suivant : 001C29

Incidental Lewy body disease: Clinical comparison to a control cohort

Auteurs : Charles H. Adler [États-Unis] ; Donald J. Connor [États-Unis] ; Joseph G. Hentz [États-Unis] ; Marwan N. Sabbagh [États-Unis] ; John N. Caviness [États-Unis] ; Holly A. Shill [États-Unis] ; Brie Noble [États-Unis] ; Thomas G. Beach [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 2010-04-15.

RBID : ISTEX:80E9546C50B3BA395A995FB31BFEB20162DF2F7E

Descripteurs français

Pascal (Inist)
- Corps Lewy, Corps Lewy maladie, Démence à corps de Lewy, Etude comparative, Maladie de Parkinson, Pathologie du système nerveux.

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Cohort Studies, Comparative study, Disability Evaluation, Female, Humans, Lewy Body Disease (diagnosis), Lewy Body Disease (physiopathology), Lewy bodies, Lewy body, Lewy body dementia, Lewy body disease, Male, Nervous system diseases, Neuropsychological Tests, Olfaction Disorders (diagnosis), Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, Retrospective Studies, Severity of Illness Index, demential with Lewy bodies, incidental Lewy body disease.
MESH :
- diagnosis : Lewy Body Disease, Olfaction Disorders, Parkinson Disease.
- physiopathology : Lewy Body Disease, Parkinson Disease.
- Aged, Aged, 80 and over, Cohort Studies, Disability Evaluation, Female, Humans, Male, Neuropsychological Tests, Retrospective Studies, Severity of Illness Index.

Abstract

Limited clinical information has been published on cases pathologically diagnosed with incidental Lewy body disease (ILBD). Standardized, longitudinal movement and cognitive data was collected on a cohort of subjects enrolled in the Sun Health Research Institute Brain and Body Donation Program. Of 277 autopsied subjects who had antemortem clinical evaluations within the previous 3 years, 76 did not have Parkinson's disease, a related disorder, or dementia of which 15 (20%) had ILBD. Minor extrapyramidal signs were common in subjects with and without ILBD. Cognitive testing revealed an abnormality in the ILBD group in the Trails B test only. ILBD cases had olfactory dysfunction; however, sample size was very small. This preliminary report revealed ILBD cases have movement and cognitive findings that for the most part were not out of proportion to similarly assessed and age‐similar cases without Lewy bodies. Larger sample size is needed to have the power to better assess group differences. © 2010 Movement Disorder Society

Url:

DOI: 10.1002/mds.22971

Affiliations:

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<front><div type="abstract" xml:lang="en">Limited clinical information has been published on cases pathologically diagnosed with incidental Lewy body disease (ILBD). Standardized, longitudinal movement and cognitive data was collected on a cohort of subjects enrolled in the Sun Health Research Institute Brain and Body Donation Program. Of 277 autopsied subjects who had antemortem clinical evaluations within the previous 3 years, 76 did not have Parkinson's disease, a related disorder, or dementia of which 15 (20%) had ILBD. Minor extrapyramidal signs were common in subjects with and without ILBD. Cognitive testing revealed an abnormality in the ILBD group in the Trails B test only. ILBD cases had olfactory dysfunction; however, sample size was very small. This preliminary report revealed ILBD cases have movement and cognitive findings that for the most part were not out of proportion to similarly assessed and age‐similar cases without Lewy bodies. Larger sample size is needed to have the power to better assess group differences. © 2010 Movement Disorder Society</div>
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Movement Disorders (revue)

Incidental Lewy body disease: Clinical comparison to a control cohort

Incidental Lewy body disease: Clinical comparison to a control cohort

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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